How do you know when it’s time to “throw in the towel” in a relationship?

If you are in a relationship and asking this question, it is possible you are already ready to throw in the towel.

Usually we know, intuitively or instinctively that the relationship has run its course. And if you are pondering the question of “how do you know”, chances are you might already be there.

Reference: https://www.quora.com/How-do-you-know-when-its-time-to-throw-in-the-towel-in-a-relationship